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When did the Human-Caused Biodiversity Decline Begin?

According to a new study carried out by an international team of scientists from Sweden, Switzerland, and the United Kingdom, the human-caused biodiversity decline started much earlier than was previously proposed, and not even by our own species, but by that of some of our ancestors millions of years ago. The study was published in the scientific journal Ecology Letters. 


Soren Faurby, a researcher at Gothenburg University and main author of the study said, “the extinctions that we see in the fossils are often explained as the results of climatic changes but the changes in Africa within the last few million years were relatively minor and our analyses show that climatic changes were not the main cause of the observed extinctions.” Computational biologist and co-author of the study, Daniele Silvestro, added, “our analyses show that the best explanation for the extinction of carnivores in East Africa is instead that they are caused by direct competition for food with our extinct ancestors.”

There were thought to be many of our common ancestors living throughout East Africa for many millions of years. And during this time, multiple extinctions are thought to have taken place. By studying African fossils, researchers can see a big reduction in the number of large carnivores, starting around 4 million years ago. It’s during this time that our ancestors are also thought to have started using a new kind of technology called kleptoparasitism in which to get food.   


Kleptoparasitism is essentially the stealing of recently slaughtered animals from other predators. On the surface, the individual animal goes hungry. But deeper than that, the whole species eventually dies out. “This may be the reason why most large carnivores in Africa have developed strategies to defend their prey,” hypothesizes Faurby. We as humans affect the planet far more today than we ever have. But, as Faurby says, “this does not mean that we previously lived in harmony with nature. Monopolization of resources is a skill we and our ancestors have had for millions of years, but only now are we able to understand and change our behavior and strive for a sustainable future. “   

Maybe Viagra’s Not as Versatile As Once Suggested

As well as being used as treatment for erectile dysfunction, Viagra is being looked at to be used in a number of other medical settings, including the treatment of fetal growth restriction (FGR). This is a condition in which babies don’t grow properly in the womb. 

However, following a recent study conducted by a group of scientists at the University of Manchester, it seems Viagra may not be as versatile as they were hoping. Because Viagra enhances blood flow it was seen as a potential choice of treatment for FGR. However, following a recent study involving mice, no real improvement was seen in terms of fetal growth, only a high blood pressure level when the pups got older. So, is the drug all it’s cracked up to be?


Perhaps not in this circumstance.

Almost 3 in every 100 pregnancies are affected by FGR. Babies that are affected and survive are more likely to suffer from developmental issues and health concerns such as diabetes and heart disease. Most of these FGR cases are caused by poor functioning of the placenta. As the blood flow becomes restricted, so does the transferring of nutrients from mother to baby. There are currently no treatments in place for FGR. For the baby to have any chance at survival, the only option is to deliver the baby early and care for it as best as possible outside of the womb. 

The results of the study conducted by the Manchester team were published in the American Journal of Physiology – Heart and Circulatory Physiology. Around the same time, an international clinical trial of Viagra and its affects on severe human FGR took place, called STRIDER. It too found no significant link between the taking of Viagra and the improvement of FGR. Unfortunately, the STRIDER trial was ground to a halt as 11 babies whose mothers were directly involved in the study and used Viagra died from lung complications. However, neither the UK-Ireland nor New Zealand trials saw any similar results.          

Going back to the Manchester study, more than 90% of baby mice whose mothers were fed Viagra while pregnant saw a hike in their blood pressure to a range similar to that of a high blood pressure level seen in humans. Female mice also saw a gain in weight after a birth and a slight reduction in their glucose intolerance after just 8 weeks. 


“The evidence from this study and others suggest that caution should be used for the use of Viagra in Fetal Growth Restriction,” said Dr. Mark Dilworth, leader of the study. “Our study suggests there may be long-term risks associated with its use in mice and importantly, there is a lack of beneficial effect in recent human clinical trials.” 

So, it seems, there is still a lot of work to be done in order to find a suitable treatment for FGR. And, it’s “important to continue to conduct studies which look at longer term impacts of giving medication during pregnancy as there is surprisingly little research on this,” concluded Dilworth. 

Using Artificial Intelligence to Ramp up the Resolution of Brain MRIs

Doctors have been using magnetic resonance imaging (MRI) on the brain for quite some time now. While it is effective in producing clear images of the human brain, there’s always room for improvement. Using artificial intelligence (AI), researchers of the ICAI Group-Computational Intelligence and Image Analysis – of the University of Malaga (UMA) have designed a new method that improves the resolution of such brain scans. 

Researchers of the ICAI Group — Computational Intelligence and Image Analysis — of the University of Malaga (UMA) have designed an unprecedented method that is capable of improving brain images obtained through magnetic resonance imaging using artificial intelligence. CREDIT University of Malaga

Using a deep learning artificial neural network, the new model boosts the quality of the image’s resolution from low to high without any distortion at all. Karl Thurnhofer, researcher and main author of the study says that it’s because of this technique, identification can be done without the help of a human. 

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The study, published in the journal Neurocomputing, represents quite a big breakthrough for science as the new model is the most accurate and efficient we’ve ever seen. “So far, the acquisition of quality brain images has depended on the time the patient remained immobilized in the scanner; with our method, image processing is carried out later on the computer,” explains Thurnhofer. Specialists can now use the algorithm to find brain-related pathologies such as cancer, physical injuries, or language disorders with much greater accuracy than ever before.   

Soybean Oil – A Healthy Choice or the Devil in Disguise?

The number one, most popular choice of cooking oil used today in the United States is soybean oil. It’s used in fast food frying, livestock feeds, and added to many packaged foods. The problem is that it’s very unhealthy. Not only does it lead to obesity and diabetes, new research has also revealed it may also affect certain neurological conditions too including depression, anxiety, autism, and Alzheimer’s disease.

Recent studies carried out at UC Riverside have revealed that soybean oil isn’t for consumption for either human or mouse. During the research mice were given three different high-fat diets. One consisted of just soybean oil. Another was made up of soybean oil that had been modified to be low in linoleic acid. While the third was coconut oil.


In 2015, the same team concluded that some of soybean oil’s detrimental health implications included the inducing of diabetes, obesity, fatty liver, and insulin resistance in mice. Then, just two year later, the same team discovered that soybean oil is much less harmful if engineered to be low in linoleic acid. But in this most recent study, there was no difference in the effect on the brain for either variant of the oil. Instead, what they did find was that a pronounced effect was taking place in the hypothalamus where many of the body’s most critical processes are carried out. 

“The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,” explained Margarita Curras-Collazo, an associate professor of neuroscience at UCR and lead author on the study. Part of the research involved determining what genes in the soybean oil fed mice weren’t working properly. The team discovered that one of these genes was responsible for producing oxytocin, otherwise known as the “love hormone”. However, in those mice given soybean oil the level of oxytocin found in the hypothalamus decreased.

Another discovery made as part of the research was that soybean oil in the diet also affected around 100 other different genes. However, the team does make it clear that this just applies to soybean oil and not to vegetable oil or other soy products. And, it should also be noted that this research was carried out on male mice and therefore the results may be different in humans. 


One thing that is yet to be determined is which chemicals in the oil are responsible for the changes they observed in the hypothalamus. All the researchers do know for sure is that it’s not linoleic acid or stigmasterol. But being able to identify the responsible compounds it a vital part of the research. As Poonamjot Deol, an assistant project scientist at UCR and first author on the study said, “this could help design healthier dietary oils in the future.” Adding to that Frances Sladek, a UCR toxicologist and professor cell biology said, “the dogma is that saturated fat is bad and unsaturated fat is good. Soybean oil is a polyunsaturated fat, but the idea that it’s good for you is just not proven.”               

What Effect does ADHD Medication have on the Brain?

One of the most common forms of attention-deficit hyperactivity disorder (ADHD) medication is a stimulant drug called methylphenidate which is used to treat symptoms such as impulsiveness, bouts of hyperactivity, and the inability to focus. And while the drug does seem to work quite well, scientists don’t fully understand why. In order to try and gain a better understanding, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) conducted a study to determine how certain areas of the brain respond to the drug which could lead to the potential development of more targeted medicine. 


No two ADHD patients will ever have the exact same responses when waiting for or receiving a reward. And neither will that of an ADHD patient and an individual without the disorder. The researchers proposed that those individuals with ADHD, released less dopamine in the brain when waiting for a reward and more when actually receiving it. “In practice, what this means is that children, or even young adults, with ADHD may have difficulty in engaging in behavior that doesn’t result in an immediate positive outcome.

For example, children may struggle to focus on schoolwork, as it may not be rewarding at the time, even though it could ultimately lead to better grades,” explained researcher and first author of the study, Dr Emi Furukawa. “Instead they get distracted by external stimuli that are novel and interesting, such as a classmate or traffic noises. 

The fMRI machine located in the IDOR imaging suite. fMRI is used to indirectly detect increased neuronal activity in an area of the brain by measuring higher levels of oxygenated to deoxygenated blood. CREDIT Andressa Dias Lemos, IDOR

Methylphenidate is thought to help those with ADHD focus by way of enhancing dopamine availability within the brain. Therefore, the team-centered their study on how the drug affects the ventral striatum, a part of the brain involved in the reward process and the release of dopamine. Using the D’Or Institute for Research and Education (IDOR)’s functional magnetic resonance imaging facility (fMRI), the researchers were able to measure the brain activity in various young adults )some with ADHD and some without) while they were playing a video game that simulated a slot machine. The ADHD individuals were scanned twice during the trial –  once when they had taken the drug and again when they had taken a placebo pill. 

Whenever the slot machine reels spun, either one of two cues were shown on the screen also. When one of the symbols was shown the individual often won money, but when the other appeared they won nothing. Therefore, the participants soon learned to associate the first symbol with that of winning money, and the second with being a non-rewarding cue. Results from the study showed that when those with ADHD took the placebo pill, neuronal activity in the ventral striatum was much the same as the response they exhibited with both the reward and non-rewarding cues. However, when methylphenidate was taken, only the reward cue increased activity in the ventral striatum, proving the individuals were capable of distinguishing between the two cues. 


Another area explored by the researchers was how neuronal activity in the medial prefrontal cortex correlated to activity within the striatum. The medial prefrontal cortex is a part of the brain that’s involved in decision-making. It receives data externally and communicates with various areas of the brain, including the striatum. When the placebo pill was taken instead of methylphenidate, there was a strong correlation between the neuronal activity in the striatum and that of the prefrontal cortex at the exact time the reward was delivered. So, the conclusion was that people with ADHD had more active communication between that of the striatum and the prefrontal cortex. This could explain the heightened sensitivity that those with ADHD experience when presented with a reward. Those who took methylphenidate and those without ADHD both had a very low activity level. 

Results from the study also indicated that a second neurotransmitter, norepinephrine, is released in the prefrontal cortex by a set of common neurons. The team has speculated that methylphenidate may boost these levels, helping to regulate dopamine levels in the striatum as rewards are delivered. “It’s becoming clear to us that the mechanism by which methylphenidate modulates the reward response is very complex,” commented Furukawa.


However, despite its complexity, the team is hopeful that further research into pinning down methylphenidate’s mechanisms of actions will benefit a lot of people worldwide. Currently there are some side effects to taking the drug which is making some people reluctant to give it to their children. If scientists can better understand the ins and outs of the drug, they may be able to better tailor it to help people without so many side effects.

3 Ways to Streamline Your Internal Business Processes

Size or sector aside, running a successful business is no easy feat. With so many organizational aspects to consider and such little time, streamlining your internal processes is essential.

While there are a wealth of organizational tools available in the digital age, without adopting the right mindset and developing a sustainable strategy to foster efficiency in all areas of your business, even the best digital tools will be of little use.

Studies show that increased organization boosts productivity. That said, if you take measures to streamline your most cumbersome internal processes, you will catalyze the success of your business, significantly.

To help you on your quest to become more efficient and as a result more productive, here are three key approaches to consider.

Analyze your existing workflow & set your business goals

To create a cohesive business ecosystem, it’s crucial to build solid organizational foundations. 

Start by gathering senior members of your team in a collaborative environment. Look at every aspect of the business, drilling down into the functions of each department, one at a time. Doing so will give you a deeper insight into your workflow, allowing you to identify any potential inefficiencies in terms of process and cross-departmental communication.


Armed with this newfound information, you will be able to set (or realign) your core business goals based on definitive key performance indicators (KPIs). 

For instance, if one of your primary goals is to make your sales and marketing department more collaborative, thereby boosting productivity by 10% in two months, you might decide to hold regular cross-departmental workshops while leveraging a digital project management platform.

Putting your workload under a microscope and setting clearcut business goals will provide you with more strategic direction, empowering your team to make informed decisions that will ultimately streamline the business for ongoing success.

Prioritize your processes & document your discoveries

Once you’ve analyzed your workload, set your business objectives, and developed a mix of potential ideas to streamline your internal affairs, you will need to prioritize your processes, documenting your ideas or solutions while you work.

Drill down deep into your business goals as well as their associated KPIs, and create a hierarchy to prioritize the areas of the organization that you feel need the most attention.

Developing a hierarchical list will help you to form a strategy to streamline every vital aspect of your business while managing your existing commitments and workload. This sure but steady approach will ensure that the initiatives you put in place are sustainable long term practices rather than short term solutions.

Moreover, prioritizing your workload methodically will give you the insight you need to understand which areas of internal operation that you can automate.

Automation software is invaluable to businesses across industries as it reduces the level of labor-intensive tasks you will have to undertake which in turn, will boost your overall output.

Manage your talent effectively

Your employees are the lifeblood of your organization. If motivation and engagement levels dwindle among your top talent, your business will suffer. And, often, employees become disengaged due to poor organizational structure. That said, to streamline your business and improve organizational efficiency across the board, managing your staff effectively is paramount. 

By leveraging scheduling software to manage your employees, you will be able to create water-tight schedules that are intuitive as well as easy to understand. Robust scheduling software also gives everyone within the organization access to the information that will empower them to manage their time better, assisting individual performance in the process.


By automating aspects of your employee management and time scheduling processes through  utilizing tools that will help you make vital improvements to your rotas, leave management initiatives, and more, you will see significant improvements to the efficiency of your business.

“Management is, above all, a practice where art, science, and craft meet.”— Henry Mintzberg

It’s clear: if you take the time to examine your existing processes without bias, lay solid organizational foundations, prioritize your plans, and leverage the power of digital technology, you will be able to streamline your business in a way that enhances productivity while empowering you to evolve your business on a sustainable basis.

For guidance on how to fortify your business against the rising threat of cybercrime, read our guide to the power of remediating vulnerabilities in real-time.

Würzburg Physicists Develop the World’s First Directional Antenna for Light

Directional antennas are used in radios in order to convert electrical signals into radio waves and then emit them in a certain direction. Not only does this enable increased performance, but it also reduces interference. Over at the University of Wurzburg’s Department of Physics, the same principle has been applied to light. In order for antennas to be able to operate with such short wavelengths of visible light they first have to be shrunk to nanometer size. And this is the basis of the research published in the journal Nature Communications.


In their publication, the researchers describe the process involved in generating directed infrared light using a gold, electrically driven Yagi-Uda antenna. For anyone who’s unsure as to what a Yagi-Uda antenna looks like, Dr. Rene Kullock, a member of the nano-optics team, has an explanation: “Basically, it works in the same way as its big brothers for radio waves. In the case of a Yagi-Uda antenna, however, this does not occur evenly in all directions but through the selective superposition of the radiated waves using special elements, the so-called reflectors and directors.” The result being constructive interference in one direction and destructive interference everywhere else. 

Let there be light – and it was directional: The world’s first electrically powered Yagi-Uda antenna was built at the University of Würzburg’s Department of Physics. CREDIT Department of Physics / JMU

Working with antenna technology on such a small scale is very challenging. It was a while ago now that the Würzburg physicists first demonstrated the principle behind an electrically driven light antenna. But some new ideas were needed in order to make the Yagi-Uda antenna a success. Much of that was down to a complex production technique in which gold was bombarded with gallium ions which then allowed the researchers to cut out the exact shape of the antenna along with all the necessary reflectors, directors, and connecting wires with high precision. Then, they carefully placed a gold nanoparticle into the element so that one wire touched the active element while the other wire was just a nanometer away.    

“This gap is so narrow that electrons can cross it when voltage is applied using a process known as “quantum tunneling”,” explained Kullock. Because of the way in which the reflectors and directors are arranged this kind of charge motion generates optical frequency vibrations within the antenna which are emitted in a specific direction. 


To have an antenna that is able to generate light in a particular direction is quite a novelty, however small as in radio wave antennas the light emissions directional accuracy is dependent on the number of antenna elements. Effectively, “this has allowed us to build the world’s smallest electrically powered light source to date which is capable of emitting light in a specific direction,” said Professor Bert Hecht, Chair of Experimental Physics 5 at the University of Würzburg. 

But much more research is needed before the invention is ready to be used commercially. Not only does more work need to be done on the counterpart that receives the light signals, but the stability and efficiency of the antenna need improving also.     

A Galactic Collision High Up in The Milky Way Creates the Birthing of Some New Stars

Some of the galaxy’s oldest stars can be found on the outskirts of the Milky Way. But in addition to those, astronomers have discovered something else – a flock of new stars. Upon investigating these stars in more depth astronomers also found that they have an extragalactic origin. It seems they were formed from the material of two nearby dwarf galaxies known as the Magellanic Clouds.

Those two galaxies are well known to astronomers already as they are on course to collide with our own. However, what researchers have recently discovered is that they’re a lot closer than previously thought.  The discovery of the new stars could provide us with a better understanding of the history of the Milky Way, including whether a collision with the Magellanic Clouds had occurred in the past.  


Being able to identify new star clusters is difficult. The galaxy is full of radiant orbs which sometimes obscure the view, making them look distorted and therefore harder to judge their distance from us. Some stars are only neighbors temporarily before swiftly moving on in the opposite direction. Figuring out which stars are clusters and which aren’t is a lengthy process that involves the recording of precise measurements over time.   

The Gaia spacecraft provided the data for the initial measurements of 1.7 billion stars. While primary discoverer Adrian Price-Whelan, a research fellow at the Flatiron’s Institute’s Center for Computational Astrophysics based in New York City, began to catalog it all. He was searching for something in particular among the dataset – blue stars. Once these were found, Price-Whelan was able to identify the cluster of stars moving next to them. After the careful cross-matching and removing of known clusters from the equation just one remained. 

A newfound cluster of young stars (blue star) sits on the periphery of the Milky Way. These stars probably formed from material originating from neighboring dwarf galaxies called the Magellanic Clouds. CREDIT D. Nidever; NASA

Aged at just 117 million years old, the newfound cluster is actually quite young for a galactic entity such as this. It’s located at the edge of the Milky Way near a river of gas called the Magellanic Stream and stretches towards the Milky Way. From their research, those working on the project proposed that the cluster originally formed while the gas emitted from the Magellanic Stream passed through the gas that surrounds the Milky Way. As this happened it created a drag force that condensed the gas enough to prompt the formation of stars. Eventually, these stars moved in front of the gas and became a part of the Milky Way. 


Judging by the current positions and movements of the stars in the cluster, it’s been estimated that the edge of the Magellanic Stream is around 90,000 light-years from that of the Milky Way. “If the Magellanic Stream is closer, especially the leading arm closest to our galaxy, then it’s likely to be incorporated into the Milky Way sooner than the current model predicts,” commented David Nidever, assistant professor of physics at Montana State University in Bozeman. 

This new research will improve current models that show where the Magellanic Clouds have been and where they’re headed to next. And with the improved numbers, we may even learn for sure whether the Magellanic Clouds passed through the Milky Way previously. Being able to answer that will greatly help astronomers better understand our own galaxy’s properties and history.     

Why Networking Monitoring Tools are Important and How to Pick One?

In today’s world, a business has to have a strong online presence to build a brand and to stay connected with the target demographic. To achieve that, it’s critical that your online network is protected against common cyber-attacks and hacking attempts so that there is minimal downtime. Network monitoring allows you to bolster your business network and also to make the most of your resources.

Your current network infrastructure can be improved in two different ways with networking monitoring. This is because you can optimize both processes and resources. With this technique, you can identify failing hardware components and network nodes, and also fix broken links that might bring down the network efficiency.


When you install a comprehensive network monitoring tool, then you can validate the network links automatically, take care of the hardware, and ensure that your network is protected from unwanted and unauthorized entities.  

How do you pick the best network monitoring tool? 

There is a slew of network monitoring tools on the internet- some are absolutely free while some come with a subscription fee. Then there are also big brands like Bitdefender whose products millions of users trust, and there are also products from less reputed brands that are less expensive but also less effective. Naturally, it can be difficult for you to make a choice but you can filter the options by keeping your objectives in mind. The following are a few factors that you can consider to make the choice easier: 

Features: An ideal network monitoring program offers several features that can come in handy, such as support for the entire IT infrastructure complete with servers, routers, etc. It should also make upscaling easier so that when your business grows, your expanding network can be monitored easily. 

Compatibility: There is no point in investing in a good networking monitoring software if it doesn’t support the hardware you are using. For instance, if you mainly use Unix-based operating systems in your company, then you should get a software that supports that OS, and if you are using Windows, then you should get a software that supports that. It’s the same concept as using Bitdefender Antivirus for Mac when you run Apple products and using a Windows antivirus when you run standard PC systems. 

Automation: Even when you have a good network monitoring software, your staff can’t keep an eye on the system 24/7. So, what you need is a program that can automate the monitoring part for you so that the staff can go on with their tasks without worrying about network vulnerabilities and the top IoT cybersecurity risks. It’s better if the program creates regular reports and logs for your consideration.


Conclusion

If you have made it this far, then you know that networking monitoring is extremely important for running an enterprise successfully. You also know the factors that you need to consider for picking the right tools for your system. So, you can get to it as soon as possible, and good luck!

Can Bitcoin Continue Its Crypto Dominance in 2020?

As we start 2020, there are the usual questions surrounding Bitcoin (BTC) that often follow the popular cryptocurrency. Such as, can BTC continue to bring value for users? Can it remain the de facto digital currency of choice? Will it face increased challenges from altcoin options that are available?

It seems Bitcoin’s reign as the leading cryptocurrency will continue into 2020 and beyond. That’s mostly because it has become so ingrained and integrated. Services are now embracing bitcoin, such casino games online for payment. Other cryptocurrency alternatives don’t have that backing. Bitcoin’s maturity is now vital to its success. 

There are still numerous competitive advantages bitcoin has and the currency will retain them through 2020. 


Fixed Supply

When comparing BTC to crypto currencies, its fixed availability is hugely important. It has become a relatively reliable source in terms of its model and production. For example, it is nearly impossible to manipulate Bitcoin’s supply. People know there are 21 million units, so the currency is unlikely to be diluted.

Why is it nearly impossible to enact changes in this way? Well, there is no current body that has the computing power that could harm the value of Bitcoin. The only way to do it would be to increase supply, and no group has the computational means to accomplish that. 

No Politics

Because Bitcoin is secure amongst cryptocurrencies, it has become a valuable denomination for anyone. As a financial means that is apolitical, the currency is even safer than hard currencies, which are often at the whim of socio-political situations. 

The politicization of traditional monetary systems is not new, but it has ramped up in recent years. Bitcoin is not affected by these changing economic tides simply because it is not controlled by any country or coalition power block. 

Technical

In terms of altcoins that could challenge BTC, Bitcoin is comfortably the most technical and technically sound. That comes with being a market leader in the crypto sector for many years. This technical prowess is exemplified by hash rate, which is better than rivals, even the popular Ethereum. 

Centralization is also important and has helped Bitcoin remain one step ahead of other networks. 


Security

Security remains a major benefit of trading in BTC because it is not centralized at all. Blockchains driven by corporations are bound by the regulations that parent organizations must adhere to. BTC does not have the problem and has no influence from political actors. 

We have seen how this will play out through the 2019 launch of Libra, a crypto developed and released by Facebook. Of course, Facebook has often been the target of regulatory clampdowns and CEO Mark Zuckerberg was forced to appear before lawmakers to defend Libra. 

The company was widely criticized for its entry into the cryptocurrency market. Most of the critiques centered on the company possibly looking to corner the crypto market through monopolization. 

Because Bitcoin is not bound to an organization, there’s no regulatory call to answer. There are no CEOs that will need to appear before regulators.