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It May Be Possible to Use Mechanical Stimulation to Regenerate Muscle

Scientists at the Wyss Institute – part of Harvard University – have determined that it may be possible to use mechanical stimulation to regenerate muscle in the future. The recent findings show that the new systems could soon replace the ones currently in place. Bioengineer David Mooney pointed out that although chemistry is the dominant science but this should change and take into account what can be gained by involving mechanical and physical factors.




Mooney led the team that was also made up of Conor Walsh a founder of the Harvard Biodesign Lab and Georg Duda of Charite-Universitatsmedizin in Berlin. Skeletal muscles cannot self-mend harsh traumas or nerve damage without muscles no longer working correctly.

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It was discovered that after cyclical mechanical stimulation, there was a 250% increase in the amount of muscle regenerated in just a couple of weeks. Lead author Christine Cezar explained that current procedures involved drugs but now stimulation is all that is needed. This knowledge allows the door to be opened to the prospect of repairing badly damaged skeletal muscles.

The result of this new study demonstrate how direct physical and mechanical intervention can impact biological processes and can potentially be exploited to improve clinical outcomes.

At a later date, the team hopes to explore how to get the ideas into the clinics. It is not yet known how this process can be transferred and used on actual patients according to Donald Ingber of the Wyss Institute.

This was not a study carried out by just a few medics but also included Ellen Roche a research fellow at the National University of Ireland, and Herman Vandenburgh, a professor at Brown University.

Original Story Via; wyss.harvard.edu




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