Tuesday, November 5, 2024
12.4 C
New York

Non-Addictive Opiod-Based Painkillers May Soon Be Coming our Way

A derivative of opium, morphine has been used for various medical purposes since ancient times and is a substance that’s issued with caution due to its very potent and addictive properties.  For years scientists have been battling on trying to find a replacement that is not as addictive or does not cause respiratory arrest with increased doses, and now, scientists at Wake Forest Baptist Medical Center may have just found the answer.





A new pain-killing compound, BU08028, has been discovered by the team that is non-addictive and shows no signs of producing any harmful side effects like other opioids available.  Professor of physiology and pharmacology at Wake Forest Baptist and lead author of the study, Mei-Chuan Ko, Ph.D states, “This is a breakthrough for opioid medicinal chemistry that we hope in the future will translate into new and safer, non-addictive pain medications.”  Despite their addictiveness and their links to respiratory arrest, mu opioid peptide (MOP) receptor agonists are still the most widely used drugs prescribed for pain relief.

During the study, 12 primates were used to test a combination of classical (MOP) and non-classical (NOP) opioid receptors.  Behavioural, physiological, and pharmalogical factors were examined and the results of the study proved that BU08028 was successful in blocking pain without the onset of any adverse side effects such as respiratory depression, itching, or cardiovascular problems.  They also discovered that the effects were long-lasting (sometimes providing up to 30 hours of pain relief) and there were no signs of physical dependence.





More News To Read

Hot this week

Brooklyn Defendants Charged in Rideshare Hacking Scheme: Jailbroken Phones Used to Exploit Uber

Brooklyn federal court has charged two defendants, Eliahou Paldiel...

Detecting Defects in Next-Generation Computer Chips: The Future of TMD-Based Semiconductors

As technology advances, the demand for smaller, more powerful...

Merging Galaxies in the Early Universe: The Birth of a Monster Galaxy

Astronomers have recently observed a fascinating event in the...

Topics

Brooklyn Defendants Charged in Rideshare Hacking Scheme: Jailbroken Phones Used to Exploit Uber

Brooklyn federal court has charged two defendants, Eliahou Paldiel...

Detecting Defects in Next-Generation Computer Chips: The Future of TMD-Based Semiconductors

As technology advances, the demand for smaller, more powerful...

Merging Galaxies in the Early Universe: The Birth of a Monster Galaxy

Astronomers have recently observed a fascinating event in the...

NASA’s Roman Space Telescope to Uncover Galactic Fossils and Dark Matter Mysteries

NASA’s Roman Space Telescope is set to transform our...

Black Myth: Wukong – A Game that Gamers Love Despite Media Backlash

In a gaming industry increasingly influenced by social agendas,...

Gravitational Waves Reveal a ‘Supercool’ Secret About the Big Bang

In 2023, physicists made a groundbreaking discovery that could...

Related Articles

Popular Categories

Send this to a friend