Cancer research is an ongoing endeavor, as scientists try to figure out how cancer cells manage to stay active and spread in a person’s body. While many treatments are aimed at alleviating symptoms and killing cancer that is present. New research is taking it a step further by finding out what exactly it is that allows cancer to thrive in the body. The body should fight against the intruder. The defenses, however, are somewhat disabled when cancer takes over. Research to help the body’s defenses kick back into full protective mode are underway.
Cancer cells are not able to spread the way they normally do when the response of chitinase 3-like-1 CHI3L1 is initiated. However, the body should be able to fight back against cancer. This ability of the cancer cells to disarm the body’s defenses needs to be shut down to stop cancer from spreading. Cancer manages to evade or co-opt the natural defenses of the body and carry on with its destruction.
All four mouse lungs had been exposed to cancer, but the two on the left were left untreated while the two on the right received an intervention that spurred one particular protein pathway to keep another in check.
The studies have reached the stage where they are being tried out on mice. Cancer manages to keep the RLH response at bay while it takes over. This RIG-like Helicase acetate is a protein that naturally has an antiviral action. The RLH pathway is something that must be accessed to keep cancer from overtaking this protein. They want to up the RLH response to fight cancer. The Poly (I:C) molecule is an RNA type of presence and can help to accomplish this task. The results are positive in the mice exposed to cancer. There has been a definitive change in the mice where this action has been applied.
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